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MICA-G129R: A bifunctional fusion protein increases PRLR-positive breast cancer cell death in co-culture with natural killer cells

Breast cancer cells were reported to up-regulate human prolactin receptor (PRLR) to assist their growth through the utilization of prolactin (PRL) as the growth factor, which makes PRLR a potential therapeutic target for breast cancer. On the other hand, advanced cancer cells tend to down-regulate o...

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Detalles Bibliográficos
Autores principales: Ding, Hui, Buzzard, Garrett W., Huang, Sisi, Sehorn, Michael G., Marcus, R. Kenneth, Wei, Yanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172023/
https://www.ncbi.nlm.nih.gov/pubmed/34077462
http://dx.doi.org/10.1371/journal.pone.0252662