Utilizing the Heterogeneity of Clinical Data for Model Refinement and Rule Discovery Through the Application of Genetic Algorithms to Calibrate a High-Dimensional Agent-Based Model of Systemic Inflammation

Introduction: Accounting for biological heterogeneity represents one of the greatest challenges in biomedical research. Dynamic computational and mathematical models can be used to enhance the study and understanding of biological systems, but traditional methods for calibration and validation commo...

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Detalles Bibliográficos
Autores principales: Cockrell, Chase, An, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172123/
https://www.ncbi.nlm.nih.gov/pubmed/34093225
http://dx.doi.org/10.3389/fphys.2021.662845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172123/
https://www.ncbi.nlm.nih.gov/pubmed/34093225
http://dx.doi.org/10.3389/fphys.2021.662845

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