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Substrate deformation regulates DRM2-mediated DNA methylation in plants

DNA methylation is a major epigenetic mechanism critical for gene expression and genome stability. In plants, domains rearranged methyltransferase 2 (DRM2) preferentially mediates CHH (H = C, T, or A) methylation, a substrate specificity distinct from that of mammalian DNA methyltransferases. Howeve...

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Detalles Bibliográficos
Autores principales: Fang, Jian, Leichter, Sarah M., Jiang, Jianjun, Biswal, Mahamaya, Lu, Jiuwei, Zhang, Zhi-Min, Ren, Wendan, Zhai, Jixian, Cui, Qiang, Zhong, Xuehua, Song, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172135/
https://www.ncbi.nlm.nih.gov/pubmed/34078593
http://dx.doi.org/10.1126/sciadv.abd9224