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The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead

Immune checkpoints (ICs) have pivotal roles in regulating immune responses. The inhibitory ICs in the tumor microenvironment (TME) have been implicated in the immune evasion of tumoral cells. Therefore, identifying and targeting these inhibitory ICs might be critical for eliminating tumoral cells. V...

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Detalles Bibliográficos
Autores principales: Hosseinkhani, Negar, Derakhshani, Afshin, Shadbad, Mahdi Abdoli, Argentiero, Antonella, Racanelli, Vito, Kazemi, Tohid, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172140/
https://www.ncbi.nlm.nih.gov/pubmed/34093577
http://dx.doi.org/10.3389/fimmu.2021.676181