Rationale and design of the OPTIMIZE trial: OPen label multicenter randomized trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients

BACKGROUND: In 2019, more than 30 % of all newly transplanted kidney transplant recipients in The Netherlands were above 65 years of age. Elderly patients are less prone to rejection, and death censored graft loss is less frequent compared to younger recipients. Elderly recipients do have increased...

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Autores principales:	de Boer, S. E., Sanders, J. S.F., Bemelman, F. J., Betjes, M. G.H., Burgerhof, J. G.M., Hilbrands, L., Kuypers, D., van Munster, B. C., Nurmohamed, S. A., de Vries, A. P.J., van Zuilen, A. D., Hesselink, D. A., Berger, S. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172178/ https://www.ncbi.nlm.nih.gov/pubmed/34078323 http://dx.doi.org/10.1186/s12882-021-02409-8