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The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel

The crystal structure of the light-gated anion channel GtACR1 reported in our previous Research Article (Li et al., 2019) revealed a continuous tunnel traversing the protein from extracellular to intracellular pores. We proposed the tunnel as the conductance channel closed by three constrictions: C1...

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Detalles Bibliográficos
Autores principales: Li, Hai, Huang, Chia-Ying, Govorunova, Elena G, Sineshchekov, Oleg A, Yi, Adrian, Rothschild, Kenneth J, Wang, Meitian, Zheng, Lei, Spudich, John L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172240/
https://www.ncbi.nlm.nih.gov/pubmed/33998458
http://dx.doi.org/10.7554/eLife.65903