Cargando…
The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel
The crystal structure of the light-gated anion channel GtACR1 reported in our previous Research Article (Li et al., 2019) revealed a continuous tunnel traversing the protein from extracellular to intracellular pores. We proposed the tunnel as the conductance channel closed by three constrictions: C1...
Autores principales: | Li, Hai, Huang, Chia-Ying, Govorunova, Elena G, Sineshchekov, Oleg A, Yi, Adrian, Rothschild, Kenneth J, Wang, Meitian, Zheng, Lei, Spudich, John L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172240/ https://www.ncbi.nlm.nih.gov/pubmed/33998458 http://dx.doi.org/10.7554/eLife.65903 |
Ejemplares similares
-
Crystal structure of the natural anion-conducting channelrhodopsin GtACR1
por: Kim, Yoon Seok, et al.
Publicado: (2018) -
Optogenetic control of the guard cell membrane potential and stomatal movement by the light-gated anion channel GtACR1
por: Huang, Shouguang, et al.
Publicado: (2021) -
Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel
por: Acharya, Anirudh R., et al.
Publicado: (2021) -
Optogenetic Stimulation Using Anion Channelrhodopsin (GtACR1) Facilitates Termination of Reentrant Arrhythmias With Low Light Energy Requirements: A Computational Study
por: Ochs, Alexander R., et al.
Publicado: (2021) -
Sequential absorption of two photons creates a bistable form of RubyACR responsible for its strong desensitization
por: Sineshchekov, Oleg A., et al.
Publicado: (2023)