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Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function

Embryonic taste bud primordia are specified as taste placodes on the tongue surface and differentiate into the first taste receptor cells (TRCs) at birth. Throughout adult life, TRCs are continually regenerated from epithelial progenitors. Sonic hedgehog (SHH) signaling regulates TRC development and...

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Detalles Bibliográficos
Autores principales: Golden, Erin J, Larson, Eric D, Shechtman, Lauren A, Trahan, G Devon, Gaillard, Dany, Fellin, Timothy J, Scott, Jennifer K, Jones, Kenneth L, Barlow, Linda A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172241/
https://www.ncbi.nlm.nih.gov/pubmed/34009125
http://dx.doi.org/10.7554/eLife.64013