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Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition
During embryogenesis, Hox mRNA translation is tightly regulated by a sophisticated molecular mechanism that combines two RNA regulons located in their 5’UTR. First, an internal ribosome entry site (IRES) enables cap-independent translation. The second regulon is a translation inhibitory element or T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172242/ https://www.ncbi.nlm.nih.gov/pubmed/34076576 http://dx.doi.org/10.7554/eLife.66369 |