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Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition

During embryogenesis, Hox mRNA translation is tightly regulated by a sophisticated molecular mechanism that combines two RNA regulons located in their 5’UTR. First, an internal ribosome entry site (IRES) enables cap-independent translation. The second regulon is a translation inhibitory element or T...

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Detalles Bibliográficos
Autores principales:	Alghoul, Fatima, Laure, Schaeffer, Eriani, Gilbert, Martin, Franck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172242/ https://www.ncbi.nlm.nih.gov/pubmed/34076576 http://dx.doi.org/10.7554/eLife.66369

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