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Employing a latent variable framework to improve efficiency in composite endpoint analysis

Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the outcomes to be classed as a responder overall. One instance of...

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Detalles Bibliográficos
Autores principales: McMenamin, Martina, Barrett, Jessica K, Berglind, Anna, Wason, James MS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172253/
https://www.ncbi.nlm.nih.gov/pubmed/33234028
http://dx.doi.org/10.1177/0962280220970986