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Employing a latent variable framework to improve efficiency in composite endpoint analysis
Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the outcomes to be classed as a responder overall. One instance of...
Autores principales: | McMenamin, Martina, Barrett, Jessica K, Berglind, Anna, Wason, James MS |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172253/ https://www.ncbi.nlm.nih.gov/pubmed/33234028 http://dx.doi.org/10.1177/0962280220970986 |
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