SARS-CoV-2 infection induces the activation of tissue factor–mediated coagulation via activation of acid sphingomyelinase

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with the hypercoagulable state. Tissue factor (TF) is the primary cellular initiator of coagulation. Most of the TF expressed on cell surfaces remains cryptic. Sphingomyelin (SM) is responsible for maintaining TF in...

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Detalles Bibliográficos
Autores principales: Wang, Jue, Pendurthi, Usha R., Yi, Guohua, Rao, L. Vijaya Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172270/
https://www.ncbi.nlm.nih.gov/pubmed/34075401
http://dx.doi.org/10.1182/blood.2021010685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172270/
https://www.ncbi.nlm.nih.gov/pubmed/34075401
http://dx.doi.org/10.1182/blood.2021010685

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