FOXO3a Protects against Kidney Injury in Type II Diabetic Nephropathy by Promoting Sirt6 Expression and Inhibiting Smad3 Acetylation

Diabetic nephropathy (DN) is the most common cause of end-stage renal disease. Although numerous reports have demonstrated a correlation between epithelial-mesenchymal transition (EMT) and renal fibrosis, how these processes lead to tubular dysfunction remains unclear. Here, we show that FOXO3a prot...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowei, Ji, Tingting, Li, Xiaoying, Qu, Xiaolei, Bai, Shoujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172321/
https://www.ncbi.nlm.nih.gov/pubmed/34122724
http://dx.doi.org/10.1155/2021/5565761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172321/
https://www.ncbi.nlm.nih.gov/pubmed/34122724
http://dx.doi.org/10.1155/2021/5565761

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