Solid-phase synthesis of d-fructose-derived Heyns peptides utilizing N(α)-Fmoc-Lysin[N(ε)-(2-deoxy-d-glucos-2-yl),N(ε)-Boc]-OH as building block

Aldoses and ketoses can glycate proteins yielding isomeric Amadori and Heyns products, respectively. Evidently, d-fructose is more involved in glycoxidation than d-glucose favoring the formation of advanced glycation endproducts (AGEs). While Amadori products and glucation have been studied extensiv...

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Detalles Bibliográficos
Autores principales: Schmutzler, Sebastian, Knappe, Daniel, Marx, Andreas, Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172402/
https://www.ncbi.nlm.nih.gov/pubmed/33934222
http://dx.doi.org/10.1007/s00726-021-02989-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172402/
https://www.ncbi.nlm.nih.gov/pubmed/33934222
http://dx.doi.org/10.1007/s00726-021-02989-7

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