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Solid-phase synthesis of d-fructose-derived Heyns peptides utilizing N(α)-Fmoc-Lysin[N(ε)-(2-deoxy-d-glucos-2-yl),N(ε)-Boc]-OH as building block

Aldoses and ketoses can glycate proteins yielding isomeric Amadori and Heyns products, respectively. Evidently, d-fructose is more involved in glycoxidation than d-glucose favoring the formation of advanced glycation endproducts (AGEs). While Amadori products and glucation have been studied extensiv...

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Detalles Bibliográficos
Autores principales:	Schmutzler, Sebastian, Knappe, Daniel, Marx, Andreas, Hoffmann, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172402/ https://www.ncbi.nlm.nih.gov/pubmed/33934222 http://dx.doi.org/10.1007/s00726-021-02989-7

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