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Control of impulsivity by G(i)-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex

Pathological impulsivity is a debilitating symptom of multiple psychiatric diseases with few effective treatment options. To identify druggable receptors with anti-impulsive action we developed a systematic target discovery approach combining behavioural chemogenetics and gene expression analysis. S...

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Detalles Bibliográficos
Autores principales: van der Veen, Bastiaan, Kapanaiah, Sampath K. T., Kilonzo, Kasyoka, Steele-Perkins, Peter, Jendryka, Martin M., Schulz, Stefanie, Tasic, Bosiljka, Yao, Zizhen, Zeng, Hongkui, Akam, Thomas, Nicholson, Janet R., Liss, Birgit, Nissen, Wiebke, Pekcec, Anton, Kätzel, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172539/
https://www.ncbi.nlm.nih.gov/pubmed/34079054
http://dx.doi.org/10.1038/s42003-021-02188-w