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Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells

In peripheral nerves, Schwann cells form myelin and provide trophic support to axons. We previously showed that the mitochondrial protein prohibitin 2 can localize to the axon-Schwann-cell interface and is required for developmental myelination. Whether the homologous protein prohibitin 1 has a simi...

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Detalles Bibliográficos
Autores principales: Della-Flora Nunes, Gustavo, Wilson, Emma R., Marziali, Leandro N., Hurley, Edward, Silvestri, Nicholas, He, Bin, O’Malley, Bert W., Beirowski, Bogdan, Poitelon, Yannick, Wrabetz, Lawrence, Feltri, M. Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172551/
https://www.ncbi.nlm.nih.gov/pubmed/34078899
http://dx.doi.org/10.1038/s41467-021-23552-8