Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre

Generating properly differentiated embryonic structures in vitro from pluripotent stem cells remains a challenge. Here we show that instruction of aggregates of mouse embryonic stem cells with an experimentally engineered morphogen signalling centre, that functions as an organizer, results in the de...

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Detalles Bibliográficos
Autores principales: Xu, Peng-Fei, Borges, Ricardo Moraes, Fillatre, Jonathan, de Oliveira-Melo, Maraysa, Cheng, Tao, Thisse, Bernard, Thisse, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172561/
https://www.ncbi.nlm.nih.gov/pubmed/34078907
http://dx.doi.org/10.1038/s41467-021-23653-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172561/
https://www.ncbi.nlm.nih.gov/pubmed/34078907
http://dx.doi.org/10.1038/s41467-021-23653-4

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