Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner

Pharmacological reversal of brain aging is a long-sought yet challenging strategy for the prevention and treatment of age-related neurodegeneration, due to the diverse cell types and complex cellular pathways impacted by the aging process. Here, we report the genome-wide reversal of transcriptomic a...

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Detalles Bibliográficos
Autores principales: Li, Zhongqi, Chen, Xinyi, Vong, Joaquim S. L., Zhao, Lei, Huang, Junzhe, Yan, Leo Y. C., Ip, Bonaventure, Wing, Yun Kwok, Lai, Hei-Ming, Mok, Vincent C. T., Ko, Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172568/
https://www.ncbi.nlm.nih.gov/pubmed/34079050
http://dx.doi.org/10.1038/s42003-021-02208-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172568/
https://www.ncbi.nlm.nih.gov/pubmed/34079050
http://dx.doi.org/10.1038/s42003-021-02208-9

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