Cargando…

Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors

Molecular dynamics of developmental processes are repurposed by cancer cells to support cancer initiation and progression. Disruption of the delicate balance between cellular differentiation and plasticity during mammary development leads to breast cancer initiation and metastatic progression. STAT5...

Descripción completa

Detalles Bibliográficos
Autores principales: Alsheikh, Heba Allah M., Metge, Brandon J., Pruitt, Hawley C., Kammerud, Sarah C., Chen, Dongquan, Wei, Shi, Shevde, Lalita A., Samant, Rajeev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172570/
https://www.ncbi.nlm.nih.gov/pubmed/34078871
http://dx.doi.org/10.1038/s41389-021-00333-y