Knockdown of Splicing Complex Protein PCBP2 Reduces Extravillous Trophoblast Differentiation Through Transcript Switching

Mutations in the LINC-HELLP non-coding RNA (HELLPAR) have been associated with familial forms of the pregnancy-specific HELLP syndrome. These mutations negatively affect extravillous trophoblast (EVT) differentiation from a proliferative to an invasive state and disturb the binding of RNA splicing c...

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Detalles Bibliográficos
Autores principales: Georgiadou, Danai, Boussata, Souad, Keijser, Remco, Janssen, Dianta A. M., Afink, Gijs B., van Dijk, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172583/
https://www.ncbi.nlm.nih.gov/pubmed/34095140
http://dx.doi.org/10.3389/fcell.2021.671806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172583/
https://www.ncbi.nlm.nih.gov/pubmed/34095140
http://dx.doi.org/10.3389/fcell.2021.671806

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