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Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet

The gut-liver axis is increasingly recognized as being involved in the pathogenesis and progression of non-alcoholic fatty liver disease (NAFLD). Prolyl endopeptidase (PREP) plays a role in gut metabolic homeostasis and neurodegenerative diseases. We investigated the role of PREP disruption in the c...

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Detalles Bibliográficos
Autores principales: Jiang, Daixi, Zhang, Jianbin, Lin, Shuangzhe, Wang, Yuqin, Chen, Yuanwen, Fan, Jiangao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172602/
https://www.ncbi.nlm.nih.gov/pubmed/34095107
http://dx.doi.org/10.3389/fcell.2021.628143