Maximizing the potential of aggressive mouse tumor models in preclinical drug testing

Atypical teratoid rhabdoid tumor (ATRT) is an aggressive embryonal brain tumor among infants and young children. Two challenges exist for preclinical testing in ATRT. First, genetically quiet, ATRT is a difficult tumor to target molecularly. Tumor cells need to divide to propagate tumor growth—inter...

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Detalles Bibliográficos
Autores principales: Elghetany, M. Tarek, Ho, Jia-Min, Shi-Qi, Lois Hew, Karthik, Sekar, Su, Jack M. F., Lin, Qi, Du, YuChen, Shen, Jianhe, Chow, Wing-Yuk, Lau, Ching C., Adesina, Adekunle, Major, Angela, Erdreich-Epstein, Anat, Hui, Kam-Man, Li, Xiao-Nan, Teo, Wan-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172610/
https://www.ncbi.nlm.nih.gov/pubmed/34079014
http://dx.doi.org/10.1038/s41598-021-91167-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172610/
https://www.ncbi.nlm.nih.gov/pubmed/34079014
http://dx.doi.org/10.1038/s41598-021-91167-6

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