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Maximizing the potential of aggressive mouse tumor models in preclinical drug testing
Atypical teratoid rhabdoid tumor (ATRT) is an aggressive embryonal brain tumor among infants and young children. Two challenges exist for preclinical testing in ATRT. First, genetically quiet, ATRT is a difficult tumor to target molecularly. Tumor cells need to divide to propagate tumor growth—inter...
Autores principales: | Elghetany, M. Tarek, Ho, Jia-Min, Shi-Qi, Lois Hew, Karthik, Sekar, Su, Jack M. F., Lin, Qi, Du, YuChen, Shen, Jianhe, Chow, Wing-Yuk, Lau, Ching C., Adesina, Adekunle, Major, Angela, Erdreich-Epstein, Anat, Hui, Kam-Man, Li, Xiao-Nan, Teo, Wan-Yee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172610/ https://www.ncbi.nlm.nih.gov/pubmed/34079014 http://dx.doi.org/10.1038/s41598-021-91167-6 |
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