Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells

Glucocappasalin (GCP), a natural product derived from the seeds of Descurainia sophia (L.) Webb. ex Prantl, exhibits potential antitumor activity in HeLa cervical carcinoma cells. In this study, we investigated the anti-cervical cancer property of GCP through the induction of cell cycle arrest, apop...

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Detalles Bibliográficos
Autores principales: Xu, Guangya, Yan, Xueling, Hu, Zhongjia, Zheng, Lulu, Ding, Ke, Zhang, Yamei, Qing, Yi, Liu, Tao, Cheng, Lijia, Shi, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172611/
https://www.ncbi.nlm.nih.gov/pubmed/34093198
http://dx.doi.org/10.3389/fphar.2021.671138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172611/
https://www.ncbi.nlm.nih.gov/pubmed/34093198
http://dx.doi.org/10.3389/fphar.2021.671138

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