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Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells
Glucocappasalin (GCP), a natural product derived from the seeds of Descurainia sophia (L.) Webb. ex Prantl, exhibits potential antitumor activity in HeLa cervical carcinoma cells. In this study, we investigated the anti-cervical cancer property of GCP through the induction of cell cycle arrest, apop...
Autores principales: | Xu, Guangya, Yan, Xueling, Hu, Zhongjia, Zheng, Lulu, Ding, Ke, Zhang, Yamei, Qing, Yi, Liu, Tao, Cheng, Lijia, Shi, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172611/ https://www.ncbi.nlm.nih.gov/pubmed/34093198 http://dx.doi.org/10.3389/fphar.2021.671138 |
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