Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1

Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related death and has a poor prognosis worldwide, thus, more effective drugs are urgently needed. In this article, a small molecule drug library composed of 1,056 approved medicines from the FDA was used to screen for antican...

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Detalles Bibliográficos
Autores principales: Zheng, Cancan, Zhu, Yidong, Liu, Qinwen, Luo, Tingting, Xu, Wenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172778/
https://www.ncbi.nlm.nih.gov/pubmed/34093212
http://dx.doi.org/10.3389/fphar.2021.689767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172778/
https://www.ncbi.nlm.nih.gov/pubmed/34093212
http://dx.doi.org/10.3389/fphar.2021.689767

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