NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA

Autophagy regulates primary cilia formation, but the underlying mechanism is not fully understood. In this study, we identify NIMA-related kinase 9 (NEK9) as a GABARAPs-interacting protein and find that NEK9 and its LC3-interacting region (LIR) are required for primary cilia formation. Mutation in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Yasuhiro, Chino, Haruka, Tsukamoto, Satoshi, Ode, Koji L., Ueda, Hiroki R., Mizushima, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172835/
https://www.ncbi.nlm.nih.gov/pubmed/34078910
http://dx.doi.org/10.1038/s41467-021-23599-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172835/
https://www.ncbi.nlm.nih.gov/pubmed/34078910
http://dx.doi.org/10.1038/s41467-021-23599-7

Ejemplares similares