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NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA
Autophagy regulates primary cilia formation, but the underlying mechanism is not fully understood. In this study, we identify NIMA-related kinase 9 (NEK9) as a GABARAPs-interacting protein and find that NEK9 and its LC3-interacting region (LIR) are required for primary cilia formation. Mutation in t...
Autores principales: | Yamamoto, Yasuhiro, Chino, Haruka, Tsukamoto, Satoshi, Ode, Koji L., Ueda, Hiroki R., Mizushima, Noboru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172835/ https://www.ncbi.nlm.nih.gov/pubmed/34078910 http://dx.doi.org/10.1038/s41467-021-23599-7 |
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