An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β

A key hallmark of Alzheimer’s disease is the extracellular deposition of amyloid plaques composed primarily of the amyloidogenic amyloid-β (Aβ) peptide. The Aβ peptide is a product of sequential cleavage of the Amyloid Precursor Protein, the first step of which gives rise to a C-terminal Fragment (C...

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Detalles Bibliográficos
Autores principales: Vadukul, Devkee M., Vrancx, Céline, Burguet, Pierre, Contino, Sabrina, Suelves, Nuria, Serpell, Louise C., Quinton, Loïc, Kienlen-Campard, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172837/
https://www.ncbi.nlm.nih.gov/pubmed/34078941
http://dx.doi.org/10.1038/s41598-021-90680-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172837/
https://www.ncbi.nlm.nih.gov/pubmed/34078941
http://dx.doi.org/10.1038/s41598-021-90680-y

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