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Intrinsic basis of thermostability of prolyl oligopeptidase from Pyrococcus furiosus
Salt-bridges play a key role in the thermostability of proteins adapted in stress environments whose intrinsic basis remains to be understood. We find that the higher hydrophilicity of PfP than that of HuP is due to the charged but not the polar residues. The primary role of these residues is to enh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172842/ https://www.ncbi.nlm.nih.gov/pubmed/34078944 http://dx.doi.org/10.1038/s41598-021-90723-4 |