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Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency

Immune checkpoint inhibitors (ICIs) are potent therapeutic options for many types of advanced cancer. The expansion of ICIs use however has led to an increase in immune-related adverse events (irAEs). Secondary adrenal insufficiency (AI) can be life-threatening especially in patients with delayed di...

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Detalles Bibliográficos
Autores principales: Manaka, Katsunori, Sato, Junichiro, Takeuchi, Maki, Watanabe, Kousuke, Kage, Hidenori, Kawai, Taketo, Sato, Yusuke, Miyagawa, Takuya, Yamada, Daisuke, Kume, Haruki, Sato, Shinichi, Nagase, Takahide, Iiri, Taroh, Nangaku, Masaomi, Makita, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172846/
https://www.ncbi.nlm.nih.gov/pubmed/34078988
http://dx.doi.org/10.1038/s41598-021-91032-6