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FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila

Target of Rapamycin Complex 1 (TORC1) is a master regulator that coordinates nutrient status with cell metabolism. The GTPase-activating protein towards Rags complex 1 (GATOR1) inhibits TORC1 activity and protects cells from damage during periods of stress. Here we characterize multiple pathways tha...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Guo, Jian, Wang, Xinyu, Cheng, Yang, Guan, Jianwen, Barman, Priyam, Sun, Ming-An, Fu, Yuanyuan, Wei, Wanhong, Feng, Congjing, Lilly, Mary A., Wei, Youheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172852/
https://www.ncbi.nlm.nih.gov/pubmed/34078879
http://dx.doi.org/10.1038/s41419-021-03860-z