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Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation

Calcium dynamics control synaptic transmission. Calcium triggers synaptic vesicle fusion, determines release probability, modulates vesicle recycling, participates in long-term plasticity and regulates cellular metabolism. Mitochondria, the main source of cellular energy, serve as calcium signaling...

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Detalles Bibliográficos
Autores principales: Stavsky, Alexandra, Stoler, Ohad, Kostic, Marko, Katoshevsky, Tomer, Assali, Essam A., Savic, Ivana, Amitai, Yael, Prokisch, Holger, Leiz, Steffen, Daumer-Haas, Cornelia, Fleidervish, Ilya, Perocchi, Fabiana, Gitler, Daniel, Sekler, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172942/
https://www.ncbi.nlm.nih.gov/pubmed/34079053
http://dx.doi.org/10.1038/s42003-021-02114-0