Lactoferrin Retargets Human Adenoviruses to TLR4 to Induce an Abortive NLRP3-Associated Pyroptotic Response in Human Phagocytes

Despite decades of clinical and preclinical investigations, we still poorly grasp our innate immune response to human adenoviruses (HAdVs) and their vectors. In this study, we explored the impact of lactoferrin on three HAdV types that are being used as vectors for vaccines. Lactoferrin is a secrete...

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Detalles Bibliográficos
Autores principales: Chéneau, Coraline, Eichholz, Karsten, Tran, Tuan Hiep, Tran, Thi Thu Phuong, Paris, Océane, Henriquet, Corinne, Bajramovic, Jeffrey J., Pugniere, Martine, Kremer, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173049/
https://www.ncbi.nlm.nih.gov/pubmed/34093588
http://dx.doi.org/10.3389/fimmu.2021.685218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173049/
https://www.ncbi.nlm.nih.gov/pubmed/34093588
http://dx.doi.org/10.3389/fimmu.2021.685218

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