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Computational Modeling as a Tool to Investigate PPI: From Drug Design to Tissue Engineering

Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the features of PPI binding surfaces make the use of structure-based drug discovery methods very challengi...

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Detalles Bibliográficos
Autores principales: Perez, Juan J., Perez, Roman A., Perez, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173110/
https://www.ncbi.nlm.nih.gov/pubmed/34095231
http://dx.doi.org/10.3389/fmolb.2021.681617