A Novel UPLC-MS/MS Assay for the Measurement of Linezolid and its Metabolite PNU-142300 in Human Serum and its Application to Patients With Renal Insufficiency

The contribution of the metabolites of linezolid to the associated myelosuppression is unknown in patients who are renal impairment. In this research, the purpose of our experiment was to explore and develop a quick and robust ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS...

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Detalles Bibliográficos
Autores principales: Wang, Yingying, Gu, Er-min, Du, Xiaoxiang, Xu, Ren-ai, Lin, Guanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173121/
https://www.ncbi.nlm.nih.gov/pubmed/34093181
http://dx.doi.org/10.3389/fphar.2021.641872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173121/
https://www.ncbi.nlm.nih.gov/pubmed/34093181
http://dx.doi.org/10.3389/fphar.2021.641872

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