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A Novel UPLC-MS/MS Assay for the Measurement of Linezolid and its Metabolite PNU-142300 in Human Serum and its Application to Patients With Renal Insufficiency
The contribution of the metabolites of linezolid to the associated myelosuppression is unknown in patients who are renal impairment. In this research, the purpose of our experiment was to explore and develop a quick and robust ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS...
Autores principales: | Wang, Yingying, Gu, Er-min, Du, Xiaoxiang, Xu, Ren-ai, Lin, Guanyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173121/ https://www.ncbi.nlm.nih.gov/pubmed/34093181 http://dx.doi.org/10.3389/fphar.2021.641872 |
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