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The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis

Retinal ischemia is a common pathological event that can result in retinal ganglion cell (RGC) death and irreversible vision loss. The pathogenic mechanisms linking retinal ischemia to RGC loss and visual deficits are uncertain, which has greatly hampered the development of effective treatments. It...

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Detalles Bibliográficos
Autores principales: Deng, Yang, Fu, Yunzhao, Sheng, Longxiang, Hu, Yixin, Su, Lishi, Luo, Jiawen, Yan, Chun, Chi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173141/
https://www.ncbi.nlm.nih.gov/pubmed/34095138
http://dx.doi.org/10.3389/fcell.2021.669696