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Salubrinal Exposes Anticancer Properties in Inflammatory Breast Cancer Cells by Manipulating the Endoplasmic Reticulum Stress Pathway

The endoplasmic reticulum (ER) regulates protein folding, post-translational modifications, lipid synthesis, and calcium signaling to attenuate the accumulation of misfolded proteins causing ER stress and maintains cellular homeostasis. The tumor microenvironment is rich in soluble cytokines, chemok...

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Detalles Bibliográficos
Autores principales: Alsterda, Andrew, Asha, Kumari, Powrozek, Olivia, Repak, Miroslava, Goswami, Sudeshna, Dunn, Alexandra M., Memmel, Heidi C., Sharma-Walia, Neelam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173155/
https://www.ncbi.nlm.nih.gov/pubmed/34094947
http://dx.doi.org/10.3389/fonc.2021.654940