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Physiologically Relevant Concentrations of Dolutegravir, Emtricitabine, and Efavirenz Induce Distinct Metabolic Alterations in HeLa Epithelial and BV2 Microglial Cells

Microglia, the resident brain phagocytes, likely play a key role in human immunodeficiency virus (HIV) infection of the central nervous system (CNS) and subsequent neuropathogenesis; however, the nature of the infection-induced changes that yield damaging CNS effects and the stimuli that provoke mic...

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Detalles Bibliográficos
Autores principales: George, Joseph W., Mattingly, Jane E., Roland, Nashanthea J., Small, Cassandra M., Lamberty, Benjamin G., Fox, Howard S., Stauch, Kelly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173175/
https://www.ncbi.nlm.nih.gov/pubmed/34093527
http://dx.doi.org/10.3389/fimmu.2021.639378