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Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release Assay

BACKGROUND: Adaptive immune responses to structural proteins of the virion play a crucial role in protection against coronavirus disease 2019 (COVID-19). We therefore studied T cell responses against multiple SARS-CoV-2 structural proteins in a large cohort using a simple, fast, and high-throughput...

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Detalles Bibliográficos
Autores principales: Brand, Isabel, Gilberg, Leonard, Bruger, Jan, Garí, Mercè, Wieser, Andreas, Eser, Tabea M., Frese, Jonathan, Ahmed, Mohamed I. M., Rubio-Acero, Raquel, Guggenbuehl Noller, Jessica M., Castelletti, Noemi, Diekmannshemke, Jana, Thiesbrummel, Sophie, Huynh, Duc, Winter, Simon, Kroidl, Inge, Fuchs, Christiane, Hoelscher, Michael, Roider, Julia, Kobold, Sebastian, Pritsch, Michael, Geldmacher, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173205/
https://www.ncbi.nlm.nih.gov/pubmed/34093595
http://dx.doi.org/10.3389/fimmu.2021.688436