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Study on the Immune Escape Mechanism of Acute Myeloid Leukemia With DNMT3A Mutation

DNA (cytosine-5)-methyltransferase 3A (DNMT3A)-mutated acute myeloid leukemia (AML) has a poor prognosis, but the exact mechanism is still unclear. Here, we aimed to explore the mechanism of immune escape in AML with DNMT3A mutation. We constructed a DNMT3A knockout clone and DNMT3A-R882H-mutated cl...

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Detalles Bibliográficos
Autores principales: Que, Yimei, Li, Huimin, Lin, Liman, Zhu, Xiaojian, Xiao, Min, Wang, Ying, Zhu, Li, Li, Dengju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173207/
https://www.ncbi.nlm.nih.gov/pubmed/34093541
http://dx.doi.org/10.3389/fimmu.2021.653030