Cargando…

Study on the Immune Escape Mechanism of Acute Myeloid Leukemia With DNMT3A Mutation

DNA (cytosine-5)-methyltransferase 3A (DNMT3A)-mutated acute myeloid leukemia (AML) has a poor prognosis, but the exact mechanism is still unclear. Here, we aimed to explore the mechanism of immune escape in AML with DNMT3A mutation. We constructed a DNMT3A knockout clone and DNMT3A-R882H-mutated cl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Que, Yimei, Li, Huimin, Lin, Liman, Zhu, Xiaojian, Xiao, Min, Wang, Ying, Zhu, Li, Li, Dengju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173207/ https://www.ncbi.nlm.nih.gov/pubmed/34093541 http://dx.doi.org/10.3389/fimmu.2021.653030

Ejemplares similares

Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway
por: Lin, Liman, et al.
Publicado: (2020)

Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study
por: Ning, Liqing, et al.
Publicado: (2020)

Editorial: The immune escape mechanism and novel immunotherapeutic strategies of leukemia
por: Yu, Kang, et al.
Publicado: (2023)

DNMT3A mutations in Chinese childhood acute myeloid leukemia
por: Li, Weijing, et al.
Publicado: (2017)

Characteristics of DNMT3A mutations in acute myeloid leukemia
por: Park, Dong Jin, et al.
Publicado: (2020)

Inflammatory abrasion of hematopoietic stem cells: a candidate clue for the post-CAR-T hematotoxicity?
por: Sun, Ting, et al.
Publicado: (2023)

The immune phenotypes and different immune escape mechanisms in colorectal cancer
por: Mao, Yihao, et al.
Publicado: (2022)

DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia
por: Lu, Quanyi, et al.
Publicado: (2013)

The methyltransferase domain of DNMT1 is an essential domain in acute myeloid leukemia independent of DNMT3A mutation
por: Bhogal, Balpreet, et al.
Publicado: (2022)

Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia
por: Jost, E, et al.
Publicado: (2014)

DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil
por: Pezzi, Annelise, et al.
Publicado: (2012)

Case report: biallelic DNMT3A mutations in acute myeloid leukemia
por: Cumbo, Cosimo, et al.
Publicado: (2023)

Immune escape mechanisms of severe fever with thrombocytopenia syndrome virus
por: Wang, Tong, et al.
Publicado: (2022)

Epigenetic landscape analysis of lncRNAs in acute myeloid leukemia with DNMT3A mutations
por: Dai, Yu-Jun, et al.
Publicado: (2020)

Prognostic impact of DNMT3A mutation in acute myeloid leukemia with mutated NPM1
por: Oñate, Guadalupe, et al.
Publicado: (2022)

The role of lysosomal peptidases in glioma immune escape: underlying mechanisms and therapeutic strategies
por: Liu, Hao, et al.
Publicado: (2023)

CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations
por: Tang, Ling, et al.
Publicado: (2022)

A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations
por: Chakraborty, Chiranjib, et al.
Publicado: (2022)

Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome
por: Lin, Jiang, et al.
Publicado: (2011)

Erratum to “DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil”
por: Pezzi, Annelise, et al.
Publicado: (2014)

Central Diabetes Insipidus Induced by Acute Myeloid Leukemia with DNMT3A Mutation
por: Lakshmanan, Priyanka, et al.
Publicado: (2022)

Mechanism of herpesvirus protein kinase UL13 in immune escape and viral replication
por: Zhou, Lin, et al.
Publicado: (2022)

Expression and prognosis analysis of DNMT family in acute myeloid leukemia
por: Zhang, Ting-Juan, et al.
Publicado: (2020)

Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia
por: Berenstein, Rimma, et al.
Publicado: (2015)

Mutational analysis of DNMT3A improves the prognostic stratification of patients with acute myeloid leukemia
por: Wakita, Satoshi, et al.
Publicado: (2023)

Demethylating therapy increases cytotoxicity of CD44v6 CAR-T cells against acute myeloid leukemia
por: Tang, Ling, et al.
Publicado: (2023)

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
por: Shin, Sang-Yong, et al.
Publicado: (2016)

Biological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations
por: Yang, Xinrui, et al.
Publicado: (2018)

Functional Analysis of DNMT3A DNA Methyltransferase Mutations Reported in Patients with Acute Myeloid Leukemia
por: A. Khrabrova, Daria, et al.
Publicado: (2019)

NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia
por: Kuželová, Kateřina, et al.
Publicado: (2022)

Identification of Cell Type-Specific Effects of DNMT3A Mutations on Relapse in Acute Myeloid Leukemia
por: Bae, Seo-Gyeong, et al.
Publicado: (2023)

Development and Validation of a Novel Prognostic Model for Acute Myeloid Leukemia Based on Immune-Related Genes
por: Li, Ran, et al.
Publicado: (2021)

Acute Myeloid Leukemia Epigenetic Immune Escape From Nature Killer Cells by ICAM-1
por: Xiao, Yang, et al.
Publicado: (2021)

A novel prognostic classification integrating lipid metabolism and immune co-related genes in acute myeloid leukemia
por: Li, Ding, et al.
Publicado: (2023)

Association between DNMT3A Mutations and Prognosis of Adults with De Novo Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis
por: Tie, Ruxiu, et al.
Publicado: (2014)

Clinical Features and MicroRNA Expression Patterns Between AML Patients With DNMT3A R882 and Frameshift Mutations
por: Yang, Li, et al.
Publicado: (2019)

DNMT3a mutations in high-risk myelodysplastic syndrome parallel those found in acute myeloid leukemia
por: Ewalt, M, et al.
Publicado: (2011)

Incidence and Prognostic Impact of DNMT3A Mutations in Korean Normal Karyotype Acute Myeloid Leukemia Patients
por: Park, Sang Hyuk, et al.
Publicado: (2015)

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia
por: Ferreira, H J, et al.
Publicado: (2016)

Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia
por: Bruno, Samantha, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vpn8ofhq524ebhqlcp64g799i6