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An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

Intratumoral hypoxia is a widely established element of the pancreatic tumor microenvironment (TME) promoting immune escape, tumor invasion, and progression, while contributing to treatment resistance and poor survival. Despite this critical role, hypoxia is underrepresented in molecular signatures...

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Detalles Bibliográficos
Autores principales: Abou Khouzam, Raefa, Rao, Shyama Prasad, Venkatesh, Goutham Hassan, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Meylan, Maxime, Nimmakayalu, Manjunath, Terry, Stéphane, Chouaib, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173254/
https://www.ncbi.nlm.nih.gov/pubmed/34093582
http://dx.doi.org/10.3389/fimmu.2021.680435