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An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
Intratumoral hypoxia is a widely established element of the pancreatic tumor microenvironment (TME) promoting immune escape, tumor invasion, and progression, while contributing to treatment resistance and poor survival. Despite this critical role, hypoxia is underrepresented in molecular signatures...
Autores principales: | Abou Khouzam, Raefa, Rao, Shyama Prasad, Venkatesh, Goutham Hassan, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Meylan, Maxime, Nimmakayalu, Manjunath, Terry, Stéphane, Chouaib, Salem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173254/ https://www.ncbi.nlm.nih.gov/pubmed/34093582 http://dx.doi.org/10.3389/fimmu.2021.680435 |
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