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The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology

Tauopathies are a heterogenous family of progressive neurodegenerative diseases defined by the appearance of proteinaceous lesions within the brain composed of abnormally folded species of Microtubule Associated Protein Tau (tau). Alzheimer’s Disease (AD), the most common tauopathy, is the leading c...

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Detalles Bibliográficos
Autores principales: Mah, Dylan, Zhao, Jing, Liu, Xinyue, Zhang, Fuming, Liu, Jian, Wang, Lianchun, Linhardt, Robert, Wang, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173255/
https://www.ncbi.nlm.nih.gov/pubmed/34095227
http://dx.doi.org/10.3389/fmolb.2021.671458