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In silico identification of novel chemical compounds with antituberculosis activity for the inhibition of InhA and EthR proteins from Mycobacterium tuberculosis

Tuberculosis (TB) continuously poses a major public health concern around the globe, with a mounting death toll of approximately 1.4 million in 2019. Reduced bioavailability, elevated toxicity, increased side effects, and resistance of multiple first-line and second-line TB medications, including is...

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Detalles Bibliográficos
Autores principales: Halder, Sajal Kumar, Elma, Fatiha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173314/
https://www.ncbi.nlm.nih.gov/pubmed/34124395
http://dx.doi.org/10.1016/j.jctube.2021.100246