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Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia

Carbohydrate metabolism in heart failure shares similarities to that following hypoxic exposure, and is thought to maintain energy homoeostasis in the face of reduced O(2) availability. As part of these in vivo adaptations during sustained hypoxia, the heart up-regulates and maintains a high glycoly...

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Detalles Bibliográficos
Autores principales: Handzlik, Michal K., Tooth, David J., Constantin-Teodosiu, Dumitru, Greenhaff, Paul L., Cole, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173528/
https://www.ncbi.nlm.nih.gov/pubmed/33973628
http://dx.doi.org/10.1042/BSR20203170